Journal article
Prediction of 10-year risk of incident heart failure in elderly hypertensive population: The ANBP2 study
BW Sahle, AJ Owen, LMH Wing, MR Nelson, GLR Jennings, CM Reid
American Journal of Hypertension | OXFORD UNIV PRESS | Published : 2017
DOI: 10.1093/ajh/hpw119
Abstract
BACKGROUND Multivariable risk prediction models consisting of routinely collected measurements can facilitate early detection and slowing of disease progression through pharmacological and nonpharmacological risk factor modifications. This study aims to develop a multivariable risk prediction model for predicting 10-year risk of incident heart failure diagnosis in elderly hypertensive population. METHODS The derivation cohort included 6083 participants aged 65 to 84 years at baseline (1995-2001) followed for a median of 10.8 years during and following the Second Australian National Blood Pressure Study (ANBP2). Cox proportional hazards models were used to develop the risk prediction models. ..
View full abstractGrants
Awarded by National Health and Medical Research Council of Australia
Awarded by NHMRC
Funding Acknowledgements
We are indebted to the participants, study staff, data management centres, and ANBP2 Management Committee. The Management Committee consists of the following members: L.M.H. Wing (Chair), C.M. Reid, L.J. Beilin, M.A. Brown, G.L.R. Jennings, C.I. Johnston, J.J. McNeil, J.E. Marley, T.O. Morgan, P. Ryan, J. Shaw (deceased), M. J. West, and G. MacDonald. ANBP2 was supported by the Australian Commonwealth Department of Health and Aging; the National Health and Medical Research Council of Australia (grant 546272); and Merck Sharp & Dohme (Australia) Pty. Ltd. The long-term ANBP2 cohort follow- up study was supported by a NHMRC program grant (546272) awarded to Henry Krum and Christopher Reid, who are also supported by NHMRC Research Fellowships (1020926 and 1045862, respectively).